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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
18.48
Human Site:
S580
Identified Species:
31.28
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S580
A
S
V
P
Q
P
A
S
P
L
M
H
I
E
G
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S580
A
S
T
P
R
P
A
S
P
L
M
H
I
E
G
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S561
A
S
A
P
R
P
A
S
P
L
M
H
I
E
G
Dog
Lupus familis
XP_543872
907
102087
S562
A
R
V
P
R
P
A
S
P
L
M
H
I
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
A532
Q
A
V
A
L
R
P
A
S
P
L
M
H
I
E
Rat
Rattus norvegicus
XP_001070646
845
94905
L510
I
E
A
F
L
E
A
L
T
T
A
N
Q
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S592
N
G
P
P
R
P
A
S
P
L
M
H
I
E
G
Chicken
Gallus gallus
XP_416375
940
105739
D592
P
P
V
E
A
D
S
D
Q
L
R
A
A
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
K539
Q
Q
M
A
V
E
D
K
P
I
M
A
S
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
S535
P
V
E
E
V
A
P
S
P
I
R
P
L
L
A
Honey Bee
Apis mellifera
XP_001121183
769
88327
V467
F
L
L
L
N
P
A
V
H
F
H
D
I
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
T478
L
N
P
A
V
H
F
T
D
V
V
K
E
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
F551
L
T
S
E
G
Q
F
F
F
E
K
N
Y
S
I
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
G666
L
T
N
L
S
S
E
G
R
I
F
Y
E
K
I
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
86.6
86.6
80
N.A.
6.6
13.3
N.A.
73.3
13.3
N.A.
13.3
N.A.
13.3
20
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
26.6
26.6
N.A.
80
20
N.A.
26.6
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
15
22
8
8
50
8
0
0
8
15
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
8
0
0
8
0
8
0
% D
% Glu:
0
8
8
22
0
15
8
0
0
8
0
0
15
36
8
% E
% Phe:
8
0
0
8
0
0
15
8
8
8
8
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
36
% G
% His:
0
0
0
0
0
8
0
0
8
0
8
36
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
22
0
0
43
8
15
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
8
8
0
8
0
% K
% Leu:
22
8
8
15
15
0
0
8
0
43
8
0
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
43
8
0
0
8
% M
% Asn:
8
8
8
0
8
0
0
0
0
0
0
15
0
0
0
% N
% Pro:
15
8
15
36
0
43
15
0
50
8
0
8
0
8
8
% P
% Gln:
15
8
0
0
8
8
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
29
8
0
0
8
0
15
0
0
0
15
% R
% Ser:
0
22
8
0
8
8
8
43
8
0
0
0
8
15
8
% S
% Thr:
0
15
8
0
0
0
0
8
8
8
0
0
0
0
0
% T
% Val:
0
8
29
0
22
0
0
8
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _